At this point of time in Canada, growing awareness of the great historical and ongoing harms of colonialism and racism demands that nursing take leadership in decolonizing the profession. Drawing on our experiences as nurses, educators and researchers and as persons who have experienced racism, we call on nursing leaders to deepen structural understanding of discrimination, make a collective commitment and shift away from "shaming and blaming" of individuals toward structural and systemic solutions. Action is required in all domains, diversifying and shifting power in every arena; revamping curriculum, practices and policies; and directly tackling racism.