Heart Research

Heart Research November -0001

Statement from the ESC regarding the ENHANCE trial

Recent media reports have kindled a controversy over the effectiveness of the combination of ezetimibe with high dose simvastatin, versus the use of simvastatin alone, in patients with familial hypercholesterolemia.
The European Society of Cardiology urges patients not to take any decisions without discussing their particular case beforehand with their physician. Patients with high cholesterol levels should not stop taking their prescribed medication.

The ENHANCE (Effects of Combination Ezetimibe and High-Dose Simvastatin versus Simvastatin Alone on the Atherosclerotic Process in Patients with Heterozygous Familial Hypercholesterolemia) trial is only one of the ongoing studies on the use of ezetimibe. The subject is being considered for discussion in our upcoming Congress and will be addressed in our peer reviewed journals.

The European Society of Cardiology (ESC):
The ESC represents nearly 53,000 cardiology professionals across Europe and the Mediterranean. Its mission is to reduce the burden of cardiovascular disease in Europe.

The ESC achieves this through a variety of scientific and educational activities including the coordination of: clinical practice guidelines, education courses and initiatives, pan-European surveys on specific disease areas and the ESC Annual Congress, the largest medical meeting in Europe. The ESC also works closely with the European Commission and WHO to improve health policy in the EU.

The ESC comprises 3 Councils, 5 Associations, 19 Working Groups, 50 National Cardiac Societies and an ESC Fellowship Community (Fellow, FESC; Nurse Fellow, NFESC). For more information on ESC Initiatives, Congresses and Constituent Bodies see www.escardio.org.

European Society of Cardiology, The European Heart House 2035 Route des Colles, B.P. 179 - Les Templiers, Sophia Antipolis F-06903 France


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