Healthcare Policy

Healthcare Policy 16(3) February 2021 : 89-105.doi:10.12927/hcpol.2021.26430
Research Paper

Understanding the Feasibility of Implementing CAR T-Cell Therapies from a Canadian Perspective

Kristina Ellis, Kelly Grindrod, Stephen Tully, Tom Mcfarlane, Kelvin K.W. Chan and William W.L. Wong

Abstract

In Canada, chimeric antigen receptor (CAR) T-cell therapy was recommended for funding for the treatment of select hematological cancers. Canadian hospitals have limited experience and capacity in administrating this therapy. We conducted a qualitative interview-based study with stakeholders in Canada. Questions were asked related to the development, administration, implementation and logistical planning of CAR T-cell therapy. Results were summarized into four main themes: (i) novel; (ii) patient characteristics and the delivery of care; (iii) processes from "bench-to-bedside"; and (iv) the future state, including both challenges and recommendations to ensure sustainability. Valuable perspectives from stakeholders highlight some of the unique challenges to implementing a highly personalized and expensive-to-deliver therapy.

 

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